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Studies was indeed analyzed from the about three-method ANOVA with pairwise assessment followed by Tukey’s blog post hoc sample

Affiliations

The primary goal of this study was to analyze urinary Na + , K + and the Na + :K + excretion ratio, for associations with changes in systolic blood pressure (SBP) in participants from the DASH–Sodium trial during the initial screening period in which participants were consuming their regular diet without dietary intervention. The secondary goals of this study were to investigate: (a) the impact of the salt sensitivity of blood pressure on these responses and (b) the impact of the DASH–Sodium dietary intervention, which lowers SBP and increases dietary K + intake, on these potential associations. Our analysis reports that in the DASH–Sodium study cohort: (1) a daily excretion of <1 g K + /day is associated with elevated SBP, (2) urinary K + excretion of >1 g/day does not correlate with a reduction in SBP and, (3) a reduction in the urinary Na + :K + excretion ratio is not associated with lower SBP irrespective of the salt sensitivity of blood pressure. Collectively our data support the recent DRI recommendation not to propose a DRI for K + and suggest that further evidence is required to support the establishment of a Na + /K + excretion ratio that would reduce SBP in the general population.

Logical variables

Suggest SBP relative to urinary sodium in order to potassium (Na + /K + ) excretion proportion during the time of testing along with dieting intervention of Weight-loss Methods to Prevent Blood pressure (DASH) large salt (HS) and you will lowest salt (LS) diet in the (a) salt delicate (n = 71), (b) salt unwilling (n = 119) individuals, viewpoints found as the imply ± SD.

Significantly, we observed no association between the urinary Na + :K + ratio and SBP on the DASH HS or DASH LS dietary https://hookupranking.com/ intervention in either SS (DASH HS R 2 = 0.04, DASH LS R 2 = 0.02) or SR (DASH HS R 2 = 0.04, DASH LS R 2 = 0.00002) participants (Fig. 5a, b). The DASH dietary intervention significantly increased the number of participants in both SS and SR groups with a urinary Na + :K + ratio of <1 on both the HS and LS diet. However, the urinary Na + :K + had no impact on SBP within dietary intake groups (Fig. 6a, b). Further, when expressed as a frequency distribution histogram the change in SBP from the DASH HS to LS dietary intervention exhibits a profound leftward shift in the SS group compared to SR group (Fig. 7a). In contrast, the frequency distribution histogram for change in the urinary Na + :K + ratio from the DASH HS to LS dietary intervention shows no difference in the Gaussian curve and distribution between SS and SR participants (Fig. 7b).

Subsequent, several studies have recommended that blood circulation pressure avoidance evoked by K + intake tends to be influenced by weight-loss Na + intake [twenty eight, 29]. Within research of one’s Dashboard-Sodium dataset we seen no connection which have urinary K + excretion and you will SBP, for the patient evaluation head to or throughout Dash dietary intervention when Na + intake try changed, recommending a freedom of your own ramifications of Na + and you can K + for the SBP contained in this studies. The brand new 2019 DRI Report concluded that there is certainly shortage of research towards the effects out of K + to the blood pressure levels and you may did not present a great DRI regarding K + . The analysis contain the 2019 DRI Report and you will suggests that dieting K + supplements may well not significantly cure blood pressure levels on standard people.

Summary

Stamler J, Flower Grams, Stamler R, Elliott P, Dyer A great, Marmot Yards. INTERSALT analysis conclusions. Public health and medical care implications. Hypertension. 1989;–eight.

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